Could coffee be the liquid key to longevity?
A new study reports that the most used stimulant in the world can extend life expectancy and affect the way cells respond to genetic damage – what has a possible complication.
A research team at the University of Queen Mary of London confirms that caffeine interacts with systems affecting aging, DNA response and cell stress.
The team studied the peaks of separation, a single-cell organism that is analogous to human cells and uses similar ways to manage energy, DNA repair and stress.
Researchers measure the response of the peaks of division to various forms of cellular stress, including DNA damage, toxic exposure and nutrient deprivation.
Then they added caffeine to evaluate how the cells will respond.
They found that while caffeine extended the life expectancy of the yeast, it also affected how the cells responded to stress, especially when the molecular systems that regulate stress were already activated.
The findings were published this week in the Microbial Cell magazine.
The research team previously proven that caffeine supports cell life expectancy by activating Tor (Rapamycin’s target), a biological switch that determines when cells should increase based on the availability of food and energy.
According to the team, Tor Switch has actively checked the responses of energy and stress in living things for over 500 million.
In this latest study, the team learned that caffeine does not run
“When your cells are low in energy, the AMPK begins to help them cope,” the high author of the study Charalampos (Babis) Rallis said. â € and our results show that caffeine helps to roll this circuit breaker.â €
The yeast model demonstrated that the impact of caffeine on the flip that switch directly affects the way cells grow, repair their DNA and respond to stress – – all of which relate to aging.
In addition, the team found that instead of protecting the damaged DNA, caffeine amplified the damage.
Typically, when a cell detects DNA damage, it stops separation to repair it. However, researchers found that caffeine exceeds this stop, allowing unealized cells to continue separation and making them more vulnerable to future damage.
The team ensured that this does not make your morning cup essentially dangerous. Caffeine’s ability to change how cells respond to problems can be positive or negative, depending on the situation.
The team noted that the benefits of caffeine depend on the presence of specific proteins and patways. The fact that the effects of caffeine are neither universal nor automatic can help explain why the previous study The link between caffeine and improved health has been in violation.
“These findings help explain why caffeine can be beneficial for health and longevity,” said John-Patrick Alao, post-doc the research scientist who runs this study. “And they open up exciting opportunities for future research on how we can promote these effects more directly – with diet, lifestyle or new medicines.”
The team admitted that because the religion of the study only at the top of the crack, the findings may not be directly translated into human cells.
Coffee has long been praised for its health benefits.
Rich in antioxidants, it can improve brain function. He also showed that it increases readiness, helping in weight management, increasing mood and potentially reduces the risk of type 2 diabetes and heart disease.
A 2018 study of nearly half a million British adults found that coffee drinks had a slightly lower risk of death over 10 years than abstaires.
Other research, including More than 170,000 adults in the UK, proposed that those who drink between two and four cups of coffee, whether they added sugar, live longer than those who do not drink coffee.
A 2025 study led by research at Tulane University then a morning production to reduce mortality rates than espresso later during the day.
And three to five glasses a day in middle life was associated with a reduced risk of Alzheimer’s disease later in life, the research stated.
In addition to Alzheimerâ, some studies found that Junkies Java have up to 60% lower risk of Parkinson’s disease.
The more coffee they drank, the lower the risk.
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